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CpelAsm

CI Docs MIT license

Description

CpelAsm is a julia package especifically desgined for haplotype allele-specific methylation based on the method in [1]. CpelAsm draws ideas from statistical physics and information theory to detect allele-specific methylation imbalances at the haplotype level.

Testing

CpelAsm is tested against Julia 1.3.0 on the latest versions of Linux, macOS and Windows.

Installation

Prerequisites

  • julia v1.3.0
  • git.

Command

CpelAsm and dependencies can be installed using the following command:

(v1.3) pkg> add https://github.com/jordiabante/CpelAsm.jl.git

Installation tests

In a julia session run

(v1.3) pkg> test CpelAsm

Authors

  • Jordi Abante

References

[1] Abante, J., Fang, Y., Feinberg, A.P., Goutsias, J., Detection of haplotype-dependent allele-specific DNA methylation in WGBS data, Nature Communications 11, 5238 (2020), https://doi.org/10.1038/s41467-020-19077-1.